Southernmost Sanctuary Vacation Rentals

Compare 7 vacation rentals.
USA > Florida > Southernmost Sanctuary

Make Southernmost Sanctuary your next getaway

Explore our vacation rentals at Southernmost Sanctuary. Our private accommodations include everything you need to have the perfect beach getaway, whether you're here for a family vacation, couples retreat, or making memories with friends.

Popular amenities for Southernmost Sanctuary vacation rentals

Popular
Dog-friendly Hot tub Internet
Osprey Suite
1 Bedroom | 1 Bath | Sleeps 4

Osprey Suite - Key West, FL

$386 avg / night 4.56 (78)
Pelican Suite
1 Bedroom | 1 Bath | Sleeps 4

Pelican Suite - Key West, FL

$418 avg / night 4.41 (56)
Heron Suite
1 Bedroom | 1 Bath | Sleeps 4

Heron Suite - Key West, FL

$404 avg / night 4.35 (62)
Ibis Suite
1 Bedroom | 1 Bath | Sleeps 4

Ibis Suite - Key West, FL

$405 avg / night 4.57 (49)
Seagull Suite
1 Bedroom | 1 Bath | Sleeps 4

Seagull Suite - Key West, FL

$398 avg / night 4.55 (80)

View 2 more homes

Browse more vacation rental amenities in Southernmost Sanctuary

A/C | Washer/dryer | Beach access | Step-free access | Enclosed yard | Snowbird-friendly

Recent Southernmost Sanctuary guest reviews

We loved this room! It’s close to the main areas of interest, great little market right around the corner, and the bike rental shop is next door as well. No need to Uber unless you are going to the airport. Rent a bike and ride around easily! Even though the road is busy, given the rooms’ location, you don’t get of the noise. We’d stay here again in a heartbeat!
Keith M. | Oct 2024
Staying here was great. Everything you need is there. Walking distance to Duval St. Close to beaches. Loved seeing the roosters in the morning.
Amy C. | Oct 2024
This place was perfect and spotless. The beds were comfortable, and having a full kitchen was a great bonus. It's just steps away from a small grocery store, a cafe, and the best bar in town, The Tipsy Rooster. It's also just a block from the ocean, and it's easy to walk throughout Old Town from this location. Checking in and out was all automated and very quick and easy as well!
Alicia H. | Aug 2024
Southernmost Sanctuary vacation rental FAQ

Yes, 7 of our Southernmost Sanctuary homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 7 of our Southernmost Sanctuary vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Southernmost Sanctuary vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Southernmost Sanctuary team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Southernmost Sanctuary, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
Vacasa Guest Value Prop Icon check-in
Seamless check-in
Vacasa Guest Value Prop Icons cleaning
Professional cleaning

Nearby destinations

Gulf Coast   |   Florida's Atlantic Coast   |   South Florida   |   Southeast Florida   |   Florida Keys   |   Lower Keys, FL   |   Old Town Key West   |   Mallory Square - Key West   |   Bahama Village - Key West   |   Key West   |   Florida
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