Southernmost Sanctuary Vacation Rentals

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USA > Florida > Southernmost Sanctuary

Make Southernmost Sanctuary your next getaway—choose from 7 great vacation rentals

Explore our vacation rentals at Southernmost Sanctuary. Our private accommodations include everything you need to have the perfect beach getaway, whether you're here for a family vacation, couples retreat, or making memories with friends.

Southernmost Sanctuary vacation rentals for every getaway

Dog-friendly Hot tub Internet
Egret Suite
0 Bedroom | 1 Bath | Sleeps 4

Egret Suite - Key West, FL

$206 avg / night
Heron Suite
0 Bedroom | 1 Bath | Sleeps 4

Heron Suite - Key West, FL

$216 avg / night
Osprey Suite
0 Bedroom | 1 Bath | Sleeps 4

Osprey Suite - Key West, FL

$195 avg / night
Ibis Suite
0 Bedroom | 1 Bath | Sleeps 4

Ibis Suite - Key West, FL

$219 avg / night
Seagull Suite
0 Bedroom | 1 Bath | Sleeps 4

Seagull Suite - Key West, FL

$220 avg / night

View 2 more homes

Recent Southernmost Sanctuary vacation rental reviews

Being on the street great location roomy clean loved it
Sherry W. | Jan 2023
We really enjoyed our stay. This place is just what my fiancé and I needed. The space was clean. The location was great very close to beaches and Duval St. while still being far enough away to be quiet and peaceful after a day of activity. I was concerned about parking in the are, however, I found plenty of free spaces in a residential area 2-3 blocks away. After that everything was only a bike ride if not walk away from the place. We enjoyed the hot tub at night and the iguana in the tree next to the door every morning. The entrance to the Osprey unit we stayed in is in a little courtyard area with tropical plants very beautiful and peaceful.
robert a. | Jan 2023
Generally speaking it’s at a really good location. We can always find parking spots (metered) in front of the unit. It’s a decent size with 2 queen beds and a full kitchen. However it depends on who are you traveling with, the location can be good or bad. There is a bar across from the street and live music every night until midnight. It’s good for anyone who wants to stay up but not for little kids that want to go to bed before 10. And in the morning at 4:30 the roosters definitely will wake you up as well. Some part of the unit will need some upgrades including the gate, the door, the shower curtain and the tower racks.
Whitney R. | Jan 2023
Southernmost Sanctuary vacation rental FAQ

Yes, 7 of our Southernmost Sanctuary homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 7 of our Southernmost Sanctuary vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our Southernmost Sanctuary vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Southernmost Sanctuary team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Southernmost Sanctuary, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning