Southernmost Sanctuary Vacation Rentals

Compare 7 vacation rentals.
USA > Florida > Southernmost Sanctuary

Make Southernmost Sanctuary your next getaway

Explore our vacation rentals at Southernmost Sanctuary. Our private accommodations include everything you need to have the perfect beach getaway, whether you're here for a family vacation, couples retreat, or making memories with friends.

Southernmost Sanctuary vacation rentals for every getaway

Dog-friendly Hot tub Internet
Egret Suite
1 Bedroom | 1 Bath | Sleeps 4

Egret Suite - Key West, FL

$318 avg / night
Southernmost Sanctuary
6 Bedroom | 6 Bath | Sleeps 24

Southernmost Sanctuary - Key West, FL

$1,680 avg / night
Pelican Suite
1 Bedroom | 1 Bath | Sleeps 4

Pelican Suite - Key West, FL

$322 avg / night
Seagull Suite
1 Bedroom | 1 Bath | Sleeps 4

Seagull Suite - Key West, FL

$322 avg / night
Heron Suite
1 Bedroom | 1 Bath | Sleeps 4

Heron Suite - Key West, FL

$321 avg / night

View 2 more homes

Recent Southernmost Sanctuary vacation rental reviews

Great big spot for family gatherings. Perfect spot.
Kenn H. | Sep 2023
Great location and perfect for a large group. We loved being able to get coffee next door and drinks across the street.
Dana W. | Sep 2023
We absolutely adored this rental! Perfect for my large batch party. It was clean (upon arrival lol), it was ready on time, and it was the best location. We had the time of our lives!
Vanessa M. | Aug 2023
Southernmost Sanctuary vacation rental FAQ

Yes, 7 of our Southernmost Sanctuary homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 7 of our Southernmost Sanctuary vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our Southernmost Sanctuary vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Southernmost Sanctuary team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Southernmost Sanctuary, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning