Key Largo Vacation Rentals

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Make Key Largo your next getaway—choose from 21 great vacation rentals

When you stay in one of our beautiful Key Largo vacation rentals, you'll enjoy front-door access to the best of the Florida Keys! Beautiful beaches, activities like diving and deep sea fishing, and a laid-back island culture make this breathtaking island the perfect destination for land and water adventurers of all ages! Key Largo is one of the most popular choices for Florida Keys vacation rentals thanks to its convenient location and variety of activities that appeals to families, couples, and retirees alike. 

Explore Key Largo house rentals, condo rentals, guest houses, and more

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House rentals

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Condo rentals

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Guest houses

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Key Largo vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
Overseas Oasis
3 Bedroom | 2.5 Bath | Sleeps 6

Overseas Oasis - Key Largo, FL

$550 avg / night
Kawama Yacht Club A4
2 Bedroom | 2 Bath | Sleeps 6

Kawama Yacht Club A4 - Key Largo, FL

$325 avg / night
Far Side of the Island
2 Bedroom | 2 Bath | Sleeps 8

Far Side of the Island - Key Largo, FL

$141 avg / night
Villa Bella
2 Bedroom | 1.5 Bath | Sleeps 6

Villa Bella - Key Largo, FL

$284 avg / night
Mariner's Retreat
4 Bedroom | 4 Bath | Sleeps 10

Mariner's Retreat - Key Largo, FL

$640 avg / night

View 16 more homes

Recent Key Largo vacation rental reviews

Fit our family perfectly
Leon T. | Aug 2022
Our stay was PERFECT! If i could give 10 stars I would. The home itself is beautiful and its fully stocked with all your needs. The host is Amazing and very helpful. The view is breathtaking and relaxing So grateful to have stayed here. Thank You !!!
JC M. | Aug 2022
The house was very spacious. Beds were very comfy. Decor is modern. Every level has a porch for enjoying the outside. Great for family of 10. Everyone has their own bathroom and space . Pools and hot tub are nice. Wish it were ocean view and parking for more than 2 cars but all else is wonderful
Carla W. | Aug 2022
Key Largo Frequently Asked Questions

Yes, 14 of our Key Largo homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 32 of our Key Largo vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Key Largo vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Key Largo team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Key Largo, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Things to do in Key Largo, FL

Whether you're longing for a relaxing getaway or hoping for an exotic escape, Key Largo is the perfect choice for your next vacation! With the Everglades National Park to the north and Islamorada and the lower Florida Keys to the south, this popular destination is ideal for outdoor adventures, island hopping, or simply soaking up the sun on the beach. 

Surrounded by the vibrant turquoise ocean, the sea offers entertainment options for both tourists and locals. Did you know that the Florida Reef is the third largest coral barrier reef in the world? Key Largo offers access to the some of the densest parts of the reef so scuba-diving or snorkeling are a popular activity on this island! Consider booking a charter fishing expedition for trophy yellowtail snapper or a sunset cruise on the calm Blackwater sound. 

Kids (and those young at heart) will love building sandcastles and playing in the sun on one of the island’s sun-drenched beaches, such as Far Beach in John Pennekamp Coral Reef Park. After splashing in the surf, enjoy some burgers or hot dogs at a family picnic on Tavernier Beach. 

From eclectic boutique shopping to the annual Humphrey Bogart Film Festival (held next to the clear blue waters Bogie navigated in the classic movie for which this island was named), there are plenty of entertainment options to choose from during your stay in one of our Key Largo vacation rentals! Although this is a family-friendly destination, the adults of the group can enjoy a happy hour pina colada at any of the island’s conch-style bars.

Outdoor adventures in Key Largo, FL

For those seeking quality time in the outdoors, the island gives up-close access to wildlife - both on land and in the water! Everglades National Park is only 37 miles away and offers daily tours. With over one million acres, this sprawling national treasure is home to a number of animal species that include alligators, crocodiles, cranes, birds, snakes, and much more. 

Key Largo boasts the title of “Dive Capital of the World” thanks to the expansive coral reef submerged just off its shores. Scuba divers can explore interesting underwater relics such as the Statue of Christ of the Abyss or the sunken Navy transport ship at Spiegel Grove without having to travel far from this beautiful island. 

Key Largo’s commitment to ecotourism and coral reef conservation means that the underwater systems of reefs, such as the Elbow, Carysfort, and Benwood reefs, can be explored by divers and appreciated by generations to come. So put on your diving gear, jump into the crystal clear waters, and explore Florida's barrier reef!

Day trips from Key Largo, FL

Key Largo is the northernmost island in the Florida Keys which makes mainland Florida very accessible at only 20 miles away. Miami, with its vibrant nightlife, Latin-inspired dining, and lovely beaches, lies just 62 miles up Highway 1. Islamorada, Marathon, and the lower keys of Big Pine and Key West are all within a 97-mile drive. This route includes driving along the Seven Mile Bridge, a famous road that offers incredible views of the ocean and wildlife. Although located a little bit further from our Key Largo vacation rentals, Florida’s east coast is known for its sightseeing, surfing opportunities, and mix of coastal cities and smaller towns.

With a beachfront location and easy access to all that the Florida Keys have to offer, our Key Largo vacation rentals are the perfect home away from home for your next getaway! 

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