Defiance Vacation Rentals

Compare 9 vacation rentals.
Home > USA > Missouri > Defiance

Make Defiance your next getaway

Defiance

Top Defiance property types

housing_type_house.jpg

House rentals

View 4 House rentals
housing_type_apartment.jpg

Apartments

View 3 Apartments
housing_type_studio.jpg

Studios

View 2 Studios

Popular amenities for Defiance vacation rentals

Popular
Internet Lake view A/C
'The Chardonnay Chalet' Defiance Studio Trail!
0 Bedroom | 1 Bath | Sleeps 3

'The Chardonnay Chalet' Defiance Studio Trail! - Defiance, MO

$121 avg / night
(excludes fees and taxes)
4.2 (5)
‘The Merlot Bungalow’ Defiance Tiny Home on Trail
0 Bedroom | 1 Bath | Sleeps 2

‘The Merlot Bungalow’ Defiance Tiny Home on Trail - Defiance, MO

$129 avg / night
(excludes fees and taxes)
4.25 (4)
'The Cabernet Cabin' Defiance Home on Katy Trail!
2 Bedroom | 1 Bath | Sleeps 4

'The Cabernet Cabin' Defiance Home on Katy Trail! - Defiance, MO

$416 avg / night
(excludes fees and taxes)
4.83 (6)
Hillside Cabin on 43 Acres w/ Private Lake & View!
1 Bedroom | 1 Bath | Sleeps 4

Hillside Cabin on 43 Acres w/ Private Lake & View! - Defiance, MO

$217 avg / night
(excludes fees and taxes)
4.82 (11)
‘The Ruebling House’ Cozy Defiance Apartment!
2 Bedroom | 2 Bath | Sleeps 6

‘The Ruebling House’ Cozy Defiance Apartment! - Defiance, MO

$213 avg / night
(excludes fees and taxes)
4.56 (9)

View 4 more homes

Recent Defiance guest reviews

The little house was clean. The shower was very good. The loft is difficult to get in and out of bed probably no way around that the way the house is built. The little couch on the first floor is comfortable. My suggestion would be to make it a pull out. The second loft looks very dangerous.
Becky . | May 2026
The Ruebling House Townview 2nd floor space was a very nice 2 bedroom space. The master suite was very spacious with attached modern bathroom with built-in shower. The guest bedroom was minimalist with small closet. Open kitchen, dining, living space was spacious. Guest bath was good size with a tub/shower with a 2 sided curtain. and a small vanity. Steps to 2nd floor was a single run, pretty steep. Conveniently across the street from Circle 6 Market & Watering Hole & a 3 minute walk to the new Saddles Social House. The Wentel’s Roadhouse next door was closed. 5 minute drive from Sugar Creek Winery, Defiance Ridge Vineyard & Chandler Hill Veneyards.
David . | Nov 2025
The location was great. We enjoyed the tiny house. It had everything we needed. We enjoyed sitting outside by the fire. There was three of us and that is about all I would put in there. It is in a RV park. The park was very clean and the bath house was also very clean.
Debbie . | Oct 2025
Defiance vacation rental FAQ

Yes. 14 of our Defiance vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Defiance vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Defiance team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Defiance, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
Vacasa Guest Value Prop Icon check-in
Seamless check-in
Vacasa Guest Value Prop Icons cleaning
Professional cleaning