Edisto Island Vacation Rentals

Compare 118 vacation rentals.
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Make Edisto Island your next getaway

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Top Edisto Island property types

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House rentals

View 85 House rentals
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Condo rentals

View 18 Condo rentals
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Duplexes

View 8 Duplexes

Popular amenities for Edisto Island vacation rentals

Popular
Dog-friendly Hot tub Internet
Dolphin Watch - A Side
6 Bedroom | 4 Bath | Sleeps 15

Dolphin Watch - A Side - Edisto Beach, SC

$572 avg / night
(excludes fees and taxes)
4.28 (151)
Just Us Edisto
4 Bedroom | 3.5 Bath | Sleeps 11

Just Us Edisto - Edisto Beach, SC

$312 avg / night
(excludes fees and taxes)
4.81 (80)
A Shore Thing
4 Bedroom | 2 Bath | Sleeps 12

A Shore Thing - Edisto Beach, SC

$483 avg / night
(excludes fees and taxes)
4.5 (184)
Oristo Haven
5 Bedroom | 4 Bath | Sleeps 11

Oristo Haven - Edisto Island, SC

$300 avg / night
(excludes fees and taxes)
Driftwood Villa 261 - Palmetto Perch
1 Bedroom | 1 Bath | Sleeps 4

Driftwood Villa 261 - Palmetto Perch - Edisto Beach, SC

$143 avg / night
(excludes fees and taxes)
4.21 (24)

View 113 more homes

Browse more vacation rental amenities in Edisto Island

Pool | Electric vehicle charger | Lake view | Lakefront | Ocean view | Oceanfront | Riverfront | Sound view | Soundfront | Water view

Recent Edisto Island guest reviews

This home is absolutely gorgeous, has plenty of amenities, is on the ocean, convenient to everything. We love having our own front yard to view the parade. There is plenty of room for our family, and everyone still has their privacy.
Catherine P. | Dec 2025
This home, decorated in coastal colors and decor, is a tranquil retreat. It was clean, recently renovated, and has comfortable beds and furniture. The view off the back deck is gorgeous with the live oaks that offer shade, some privacy and attract a variety of birds. The kitchen was well stocked with everything I needed for a week's stay.
Dawn W. | Dec 2025
Close to the playground and great walking
Susan C. | Dec 2025
Edisto Island vacation rental FAQ

Yes, 45 of our Edisto Island homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 118 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Edisto Island, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
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Seamless check-in
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Professional cleaning


Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.

Nearby destinations

Edisto Island   |   Edisto Beach   |   South Carolina
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