South Carolina Vacation Rentals

Compare 2,850 vacation rentals. Enter your trip dates to get started.
USA > South Carolina

Make South Carolina your next getaway—choose from 2,850 great vacation rentals

Welcome to the Palmetto State, where opportunities for fun in the sun are unlimited. While this distinctly Southern state has seen rough times, it’s become a restful retreat for many vacationers. Its major cities, including Charleston and Columbia, still boast a laid-back vibe, welcoming visitors to slow down, stroll historic streets, and indulge in rich Southern food. South Carolina’s many vacation destinations draw guests from near and far who travel to stay in Hilton Head beach rentals, lakefront cabins, and everything in between.

Explore South Carolina condo rentals, house rentals, studios, and more


Condo rentals

View 1,519 Condo rentals

House rentals

View 536 House rentals


View 436 Studios

South Carolina vacation rentals for every getaway

Dog-friendly Hot tub Internet
Bay Watch 1603
1 Bedroom | 1 Bath | Sleeps 6

Bay Watch 1603 - North Myrtle Beach, SC

$162 avg / night
Bay Watch 1006
1 Bedroom | 1 Bath | Sleeps 6

Bay Watch 1006 - North Myrtle Beach, SC

$141 avg / night
Carolinian Beach Resort 0706
0 Bedroom | 1 Bath | Sleeps 4

Carolinian Beach Resort 0706 - Myrtle Beach, SC

$141 avg / night
The Patricia Grand 0914
0 Bedroom | 1 Bath | Sleeps 2

The Patricia Grand 0914 - Myrtle Beach, SC

$137 avg / night
Carolinian Beach Resort 0709
0 Bedroom | 1 Bath | Sleeps 2

Carolinian Beach Resort 0709 - Myrtle Beach, SC

$134 avg / night

View 2,845 more homes

Recent South Carolina vacation rental reviews

Eric H. | Jun 2022
If you are looking for a relaxing vacation, look no further! This home is absolutely amazing! With plenty of spacious room for your family, you will have lots of things to do within walking distance to include basketball, tennis, bike trails, pools, putt putt and golf. The best part is it's only a 2 block walk to the beach and quiet neighborhood for some much needed R&R. With balconies all around, you can sit with your coffee in hand, reading a good book, while hearing the birds chirp and watching the wildlife walk around. The decor and updates throughout makes you feel like you're in an oasis! This is our 2nd time renting from the owner and most definitely won't be our last. If you're looking for a wonderful home with great views of wildlife, amazing amenities and the best customer service not only from the rental company but from the owner, look no further!! You won't regret the experience!!
Amanda T. | Jun 2022
Loved the area very close to everything very convenient!! Only thing I’d wanted it didn’t have was beach view but it’s right on beach
Rhonda B. | Jun 2022

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Beach destinations in South Carolina

If you’re looking for a beautiful South Carolina beach rental, look no further than Hilton Head Island. This wildly popular beach town is perfect for family vacations, romantic getaways, or golf retreats. Speaking of golf, Kiawah Island, farther up the coast, offers world-class golf in a beautiful resort setting.

Myrtle Beach boasts plenty of charms, too—if you’re looking to spend the winter in a South Carolina vacation rental, Myrtle Beach is the place to be. Snowbirds love spending the season at the sunny shores of Myrtle Beach, with its endless seafood, family-friendly entertainment, and relaxed atmosphere.

South Carolina lake vacations

If a lake trip is more your style, meander your way upstate to Lake Murray, one of South Carolina’s favorite lake destinations among locals and visitors alike. Columbia residents love Lake Murray as a quick getaway, at just a few miles outside the city limits. Water ski, explore the shoreline by bike, or try your luck dropping a fishing line—the options from your Lake Murray vacation rental are unlimited.

Our South Carolina vacation rentals provide a restful escape for you and your loved ones. Book today, and let the bliss begin.

Discover South Carolina

Pet-Friendly East Coast Vacations Your Dog Will Love

5 Oceanfront Hilton Head Vacation Rentals With Pools

Find the Perfect Myrtle Beach Condo Rental for You