South Carolina Vacation Rentals

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USA > South Carolina

Make South Carolina your next getaway—choose from 2,913 great vacation rentals

Welcome to the Palmetto State, where opportunities for fun in the sun are unlimited. While this distinctly Southern state has seen rough times, it’s become a restful retreat for many vacationers. Its major cities, including Charleston and Columbia, still boast a laid-back vibe, welcoming visitors to slow down, stroll historic streets, and indulge in rich Southern food. South Carolina’s many vacation destinations draw guests from near and far who travel to stay in Hilton Head beach rentals, lakefront cabins, and everything in between.

Explore South Carolina condo rentals, house rentals, studios, and more


Condo rentals

View 1,560 Condo rentals

House rentals

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View 435 Studios

South Carolina vacation rentals for every getaway

Dog-friendly Hot tub Internet
But ’N Ben
2 Bedroom | 2.5 Bath | Sleeps 6 (4 Adults Max)

But ’N Ben - Charleston, SC

$387 avg / night
The Patricia Grand 1622
0 Bedroom | 1 Bath | Sleeps 2

The Patricia Grand 1622 - Myrtle Beach, SC

$130 avg / night
Carolinian Beach Resort 0602
0 Bedroom | 1 Bath | Sleeps 4

Carolinian Beach Resort 0602 - Myrtle Beach, SC

$137 avg / night
Carolinian Beach Resort 0605
0 Bedroom | 1 Bath | Sleeps 4

Carolinian Beach Resort 0605 - Myrtle Beach, SC

$137 avg / night
Heritage Villas 2294
4 Bedroom | 3.5 Bath | Sleeps 12

Heritage Villas 2294 - Hilton Head, SC

$347 avg / night

View 2,908 more homes

Recent South Carolina vacation rental reviews

Very clean Beautiful view. Everything you can ask for on a vacation. Friendly staff great amenities at the resort
Steven F. | Aug 2022
Room 1810 provided the perfect place for my family vacation. The kitchen was well stocked with items to cook with & a toaster we used, as well as a blender & coffee pot we did not use. I was amazed with the cleanliness of the room upon arrival, as the refrigerator, microwave, stove, bathroom, carpet, everything was spotless. The room stayed very cool & comfortable. Everyone working there was always very friendly when we passed in the walkway, elevator, or when calling requesting towels. The pools were always very clean. The closet space was great with 3 closets to store all our items out of sight. Great space for a family of 5 with the sleeper sofa & nice to have doors that close between the bedroom & living room area. The oceanfront balcony was amazing to view the sunrise each morning & enjoy the sounds of the ocean, & enjoyed the view from the 18th floor. Lots of places to eat & shop within walking distance. I would highly recommend & hope to return in the future!
Leslie R. | Aug 2022
Everything was as advertised. Would definitely stay there again.
James R. | Aug 2022
South Carolina Frequently Asked Questions

Yes, 594 of our South Carolina homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 2911 of our South Carolina vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our South Carolina vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local South Carolina team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for South Carolina, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Beach destinations in South Carolina

If you’re looking for a beautiful South Carolina beach rental, look no further than Hilton Head Island. This wildly popular beach town is perfect for family vacations, romantic getaways, or golf retreats. Speaking of golf, Kiawah Island, farther up the coast, offers world-class golf in a beautiful resort setting.

Myrtle Beach boasts plenty of charms, too—if you’re looking to spend the winter in a South Carolina vacation rental, Myrtle Beach is the place to be. Snowbirds love spending the season at the sunny shores of Myrtle Beach, with its endless seafood, family-friendly entertainment, and relaxed atmosphere.

South Carolina lake vacations

If a lake trip is more your style, meander your way upstate to Lake Murray, one of South Carolina’s favorite lake destinations among locals and visitors alike. Columbia residents love Lake Murray as a quick getaway, at just a few miles outside the city limits. Water ski, explore the shoreline by bike, or try your luck dropping a fishing line—the options from your Lake Murray vacation rental are unlimited.

Our South Carolina vacation rentals provide a restful escape for you and your loved ones. Book today, and let the bliss begin.

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