South Carolina Vacation Rentals

Compare 2,282 vacation rentals. Enter your trip dates to get started.
USA > South Carolina

Make South Carolina your next getaway—choose from 2,282 great vacation rentals

Welcome to the Palmetto State, where opportunities for fun in the sun are unlimited. While this distinctly Southern state has seen rough times, it’s become a restful retreat for many vacationers. Its major cities, including Charleston and Columbia, still boast a laid-back vibe, welcoming visitors to slow down, stroll historic streets, and indulge in rich Southern food. South Carolina’s many vacation destinations draw guests from near and far who travel to stay in Hilton Head beach rentals, lakefront cabins, and everything in between.

Explore South Carolina condo rentals, house rentals, studios, and more


Condo rentals

View 1,093 Condo rentals

House rentals

View 470 House rentals


View 431 Studios

South Carolina vacation rentals for every getaway

Dog-friendly Hot tub Internet
Carolinian Beach Resort 0910 3D Tour
0 Bed | 1 Bath | Sleeps 4

Carolinian Beach Resort 0910 - Myrtle Beach, SC

From $63
Bay Watch 0814 3D Tour
1 Bed | 1 Bath | Sleeps 6

Bay Watch 0814 - North Myrtle Beach, SC

From $72
Harbourgate 0404 3D Tour
1 Bed | 1 Bath | Sleeps 4

Harbourgate 0404 - North Myrtle Beach, SC

From $70
The Patricia Grand 1012 3D Tour
0 Bed | 1 Bath | Sleeps 4

The Patricia Grand 1012 - Myrtle Beach, SC

From $67
Carolinian Beach Resort 0707 3D Tour
0 Bed | 1 Bath | Sleeps 4

Carolinian Beach Resort 0707 - Myrtle Beach, SC

From $66

View 2,277 more homes

Recent South Carolina vacation rental reviews

Great place.
Willam R. | Jul 2021
Clean, roomy villa and closest to the beach. Owner has the villa fully stocked with everything you need to relax, TV, cook and sun. Having a beach club locker rocks as it’s great to store your beach chairs, towels, etc. shipyard is much more relaxed and less crowded than Palmetto and Sea Pines. We loved it and this is our 2nd time in this villa.
Jeff D. | Jul 2021
Easy bike ride to access the beach. Quite neighborhood. Clean
eric s. | Jul 2021

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Beach destinations in South Carolina

If you’re looking for a beautiful South Carolina beach rental, look no further than Hilton Head Island. This wildly popular beach town is perfect for family vacations, romantic getaways, or golf retreats. Speaking of golf, Kiawah Island, farther up the coast, offers world-class golf in a beautiful resort setting.

Myrtle Beach boasts plenty of charms, too—if you’re looking to spend the winter in a South Carolina vacation rental, Myrtle Beach is the place to be. Snowbirds love spending the season at the sunny shores of Myrtle Beach, with its endless seafood, family-friendly entertainment, and relaxed atmosphere.

South Carolina lake vacations

If a lake trip is more your style, meander your way upstate to Lake Murray, one of South Carolina’s favorite lake destinations among locals and visitors alike. Columbia residents love Lake Murray as a quick getaway, at just a few miles outside the city limits. Water ski, explore the shoreline by bike, or try your luck dropping a fishing line—the options from your Lake Murray vacation rental are unlimited.

Our South Carolina vacation rentals provide a restful escape for you and your loved ones. Book today, and let the bliss begin.

Discover South Carolina

Pet-Friendly East Coast Vacations Your Dog Will Love

5 Oceanfront Hilton Head Vacation Rentals With Pools

Find the Perfect Myrtle Beach Condo Rental for You