South Carolina Vacation Rentals

Compare 2,895 vacation rentals with savings up to 30% off this summer.
USA > South Carolina

Make South Carolina your next getaway

Welcome to the Palmetto State, where opportunities for fun in the sun are unlimited. While this distinctly Southern state has seen rough times, it’s become a restful retreat for many vacationers. Its major cities, including Charleston and Columbia, still boast a laid-back vibe, welcoming visitors to slow down, stroll historic streets, and indulge in rich Southern food. South Carolina’s many vacation destinations draw guests from near and far who travel to stay in Hilton Head beach rentals, lakefront cabins, and everything in between.

Explore South Carolina condo rentals, house rentals, studios, and more


Condo rentals

View 1,594 Condo rentals

House rentals

View 522 House rentals


View 421 Studios

South Carolina vacation rentals for every getaway

Dog-friendly Hot tub Internet
The Patricia Grand 0524
0 Bedroom | 1 Bath | Sleeps 4

The Patricia Grand 0524 - Myrtle Beach, SC

$114 avg / night
The Patricia Grand 0618
0 Bedroom | 1 Bath | Sleeps 2

The Patricia Grand 0618 - Myrtle Beach, SC

$111 avg / night
The Patricia Grand 0530
0 Bedroom | 1 Bath | Sleeps 4

The Patricia Grand 0530 - Myrtle Beach, SC

$113 avg / night
The Patricia Grand 1916
0 Bedroom | 1 Bath | Sleeps 2

The Patricia Grand 1916 - Myrtle Beach, SC

$122 avg / night
The Patricia Grand 1636
0 Bedroom | 1 Bath | Sleeps 4

The Patricia Grand 1636 - Myrtle Beach, SC

$112 avg / night

View 2,890 more homes

Recent South Carolina vacation rental reviews

This was our third time in this home we love how convenient it is to the beach and how clean and well maintained it is. We will definitely be returning again to the same home.
Annette L. | Jun 2023
It was very clean and the kitchen was well stocked. I would stay here again.
Shannon O. | Jun 2023
Easy check in and check out. The room had a beautiful view of the ocean and the room was very clean. Kitchen was stocked with pots, pans, eating and cooking utensils, plates, bowls, and cups. My only complaint is the bed are very firm
Toni K. | Jun 2023
South Carolina vacation rental FAQ

Yes, 613 of our South Carolina homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 2893 of our South Carolina vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our South Carolina vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local South Carolina team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for South Carolina, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Beach destinations in South Carolina

If you’re looking for a beautiful South Carolina beach rental, look no further than Hilton Head Island. This wildly popular beach town is perfect for family vacations, romantic getaways, or golf retreats. Speaking of golf, Kiawah Island, farther up the coast, offers world-class golf in a beautiful resort setting.

Myrtle Beach boasts plenty of charms, too—if you’re looking to spend the winter in a South Carolina vacation rental, Myrtle Beach is the place to be. Snowbirds love spending the season at the sunny shores of Myrtle Beach, with its endless seafood, family-friendly entertainment, and relaxed atmosphere.

South Carolina lake vacations

If a lake trip is more your style, meander your way upstate to Lake Murray, one of South Carolina’s favorite lake destinations among locals and visitors alike. Columbia residents love Lake Murray as a quick getaway, at just a few miles outside the city limits. Water ski, explore the shoreline by bike, or try your luck dropping a fishing line—the options from your Lake Murray vacation rental are unlimited.

Our South Carolina vacation rentals provide a restful escape for you and your loved ones. Book today, and let the bliss begin.

Discover South Carolina

Pet-Friendly East Coast Vacations Your Dog Will Love

5 Oceanfront Hilton Head Vacation Rentals With Pools

Find the Perfect Myrtle Beach Condo Rental for You

Travel Guide: Things to Do in Charleston, SC

Travel Guide: Things to Do in Myrtle Beach, SC

6 Top Spots for Surf Vacation Homes