Edisto Island Vacation Rentals

Compare 118 vacation rentals.
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Make Edisto Island your next getaway

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Top Edisto Island property types

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House rentals

View 85 House rentals
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Condo rentals

View 17 Condo rentals
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Duplexes

View 9 Duplexes

Popular amenities for Edisto Island vacation rentals

Popular
Dog-friendly Hot tub Internet
Heh Edisto
3 Bedroom | 2 Bath | Sleeps 6

Heh Edisto - Edisto Beach, SC

$188 avg / night
(excludes fees and taxes)
4.56 (50)
Oristo Haven
5 Bedroom | 4 Bath | Sleeps 11

Oristo Haven - Edisto Island, SC

$324 avg / night
(excludes fees and taxes)
5.0 (1)
Barefoot Lizzy
3 Bedroom | 2 Bath | Sleeps 8

Barefoot Lizzy - Edisto Beach, SC

$235 avg / night
(excludes fees and taxes)
4.67 (49)
Bay Creek Villa 304 - Just Coastin'
2 Bedroom | 2 Bath | Sleeps 4

Bay Creek Villa 304 - Just Coastin' - Edisto Beach, SC

$185 avg / night
(excludes fees and taxes)
4.87 (39)
Happy Place
2 Bedroom | 1.5 Bath | Sleeps 5

Happy Place - Edisto Beach, SC

$206 avg / night
(excludes fees and taxes)
4.76 (25)

View 113 more homes

Browse more vacation rental amenities in Edisto Island

Pool | Electric vehicle charger | Lake view | Lakefront | Ocean view | Oceanfront | Riverfront | Sound view | Soundfront | Water view

Recent Edisto Island guest reviews

Close to beach and Whaleys. Walking distance. Clean home with lots of space and parking.
Glynna F. | Jan 2026
The Location. The cleanliness. The space.
Ken H. | Jan 2026
Condo was close to recreational areas. The recliners are very comfortable. There is a good selection of pots for cooking. Toiletries provided in large bottles mounted on wall of shower/bathtub. We weren’t expecting 42 steps/stairs to climb to 3rd floor. Got easier to climb every day. Clean and convenient.
Harriet F. | Jan 2026
Edisto Island vacation rental FAQ

Yes, 44 of our Edisto Island homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 118 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Edisto Island, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
Vacasa Guest Value Prop Icon check-in
Seamless check-in
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Professional cleaning


Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.

Nearby destinations

Edisto Island   |   Edisto Beach   |   South Carolina
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