Edisto Island Vacation Rentals

Compare 130 vacation rentals.
USA > South Carolina > Edisto Island

Make Edisto Island your next getaway

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Explore Edisto Island house rentals, condo rentals, villas, and more


House rentals

View 104 House rentals

Condo rentals

View 14 Condo rentals


View 4 Villas

Edisto Island vacation rentals for every getaway

Dog-friendly Hot tub Internet
The Answer
4 Bedroom | 3 Bath | Sleeps 12

The Answer - Edisto Beach, SC

$314 avg / night
A Shore Thing
4 Bedroom | 2 Bath | Sleeps 11

A Shore Thing - Edisto Beach, SC

$560 avg / night
Summer Place
5 Bedroom | 3 Bath | Sleeps 12

Summer Place - Edisto Beach, SC

$526 avg / night
Sunrise, Sunset
4 Bedroom | 2 Bath | Sleeps 13

Sunrise, Sunset - Edisto Beach, SC

$600 avg / night
Barefoot Lizzy
3 Bedroom | 2 Bath | Sleeps 8

Barefoot Lizzy - Edisto Beach, SC

$240 avg / night

View 125 more homes

Recent Edisto Island vacation rental reviews

Great view of golf course. Easy access from vehicle. Very cozy. We will definitely stay there again
Mary H. | Mar 2024
Quiet beach house. House exactly as advertised. Loved the deck with ocean view. Beach was perfect for walking and shell hunting. Tried shore fishing and caught a few ocean fish. Saw lots of dolphins and pelicans. Found sand dollars. Perfect relaxing vacation
Sue C. | Feb 2024
The house was fantastic. A short walk to the beach access and the beach.
Michael M. | Feb 2024
Edisto Island vacation rental FAQ

Yes, 60 of our Edisto Island homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 130 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Edisto Island, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.