Edisto Island Vacation Rentals

Compare 133 vacation rentals.
USA > South Carolina > Edisto Island

Make Edisto Island your next getaway

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Explore Edisto Island house rentals, condo rentals, cottages, and more


House rentals

View 108 House rentals

Condo rentals

View 15 Condo rentals


View 3 Cottages

Popular amenities for Edisto Island vacation rentals

Dog-friendly Hot tub Internet
Champagne and Sunsets
3 Bedroom | 2 Bath | Sleeps 6

Champagne and Sunsets - Edisto Beach, SC

$306 avg / night
Driftwood Villa 261 - Palmetto Perch
1 Bedroom | 1 Bath | Sleeps 4

Driftwood Villa 261 - Palmetto Perch - Edisto Beach, SC

$157 avg / night
Toes in the Sand
4 Bedroom | 2 Bath | Sleeps 10

Toes in the Sand - Edisto Beach, SC

$241 avg / night
Sunrise, Sunset
4 Bedroom | 2 Bath | Sleeps 13

Sunrise, Sunset - Edisto Beach, SC

$592 avg / night
Driftwood Villa  262
1 Bedroom | 1 Bath | Sleeps 4

Driftwood Villa 262 - Edisto Beach, SC

$154 avg / night

View 128 more homes

Recent Edisto Island guest reviews

Modern, not cluttered, clean, well equipped with bare necessities. We liked hardwood floor panels and no carpets at all, bright rooms and decor, the fact that you could have a dog there. Beautiful view from the screened back porch. We enjoyed the keyless entry (no keys to carry around!), a private outdoor shower for cleaning up from the beach sand. There is a gas grill - we liked that too, even though the preference is a charcoal one. Close to the beach, 5 min. walk. We will be back.
Maciej N. | May 2024
Everything was great! Will definitely be booking again
Bradan T. | May 2024
Very nice kitchen . Love the remodeled look of the house
Phyllis B. | May 2024
Edisto Island vacation rental FAQ

Yes, 60 of our Edisto Island homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 133 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Edisto Island, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.