Edisto Island Vacation Rentals

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USA > South Carolina > Edisto Island

Make Edisto Island your next getaway—choose from 117 great vacation rentals

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Explore Edisto Island house rentals, condo rentals, villas, and more


House rentals

View 101 House rentals

Condo rentals

View 8 Condo rentals


View 3 Villas

Edisto Island vacation rentals for every getaway

Dog-friendly Hot tub Internet
Caretta Cottage
2 Bedroom | 2 Bath | Sleeps 5

Caretta Cottage - Edisto Beach, SC

$202 avg / night
1 Bedroom | 1 Bath | Sleeps 3

Sea-Esta - Edisto Beach, SC

$123 avg / night
Driftwood Villa - 234  Driftwood Dream
2 Bedroom | 1 Bath | Sleeps 6

Driftwood Villa - 234 Driftwood Dream - Edisto Beach, SC

$147 avg / night
Driftwood Villa - 264  Blessed Rest
2 Bedroom | 1 Bath | Sleeps 5

Driftwood Villa - 264 Blessed Rest - Edisto Beach, SC

$176 avg / night
Turtle Pond
3 Bedroom | 2 Bath | Sleeps 6

Turtle Pond - Edisto Beach, SC

$252 avg / night

View 112 more homes

Recent Edisto Island vacation rental reviews

View was amazing as always. Tons of games and plenty of cookware for cooking in. King bed was a little hard but other than that everything was great!
Victoria T. | Mar 2023
This house was perfect. Never been to Edisto and was just amazed. We loved the house I love to cook and this kitchen with all the utensils and pots and pans. And the size of the kitchen. Loved it will be back
Elizabeth T. | Mar 2023
Our family had an amazing week at the Blue Pelican. The home was so clean and beautifully decorated. Plenty of space for everyone! Kitchen was well equipped with new appliances. Furnishings were very comfortable. We enjoyed catching many fish from the dock and the short walk to the beach. Cornhole was a big hit, we enjoyed our nightly tournaments. Grateful we were able to bring our furbaby, she had a great time at the beach!
Stacey E. | Mar 2023
Edisto Island vacation rental FAQ

Yes, 55 of our Edisto Island homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 116 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Edisto Island, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.