Edisto Island Vacation Rentals

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USA > South Carolina > Edisto Island

Make Edisto Island your next getaway—choose from 115 great vacation rentals

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Explore Edisto Island house rentals, condo rentals, cottages, and more


House rentals

View 104 House rentals

Condo rentals

View 5 Condo rentals


View 2 Cottages

Edisto Island vacation rentals for every getaway

Dog-friendly Hot tub Internet
Caretta Cottage
2 Bedroom | 2 Bath | Sleeps 5

Caretta Cottage - Edisto Beach, SC

$195 avg / night
1 Bedroom | 1 Bath | Sleeps 2

Sea-Esta - Edisto Beach, SC

$119 avg / night
Driftwood Villa - 234  Driftwood Dream
2 Bedroom | 1 Bath | Sleeps 4

Driftwood Villa - 234 Driftwood Dream - Edisto Beach, SC

$143 avg / night
Driftwood Villa - 264  Blessed Rest
2 Bedroom | 1 Bath | Sleeps 5

Driftwood Villa - 264 Blessed Rest - Edisto Beach, SC

$153 avg / night
Turtle Pond
3 Bedroom | 2 Bath | Sleeps 6

Turtle Pond - Edisto Beach, SC

$220 avg / night

View 110 more homes

Recent Edisto Island vacation rental reviews

I’m coming back!!!!
Jim M. | Nov 2022
This house is a great get-away location. Beautiful views and very comfortable living spaces. Great for a quiet escape with your family.
Jerry M. | Nov 2022
There was room for our 12 to have plenty of group time and places to go when space was needed. Super close to the beach too!
Chris C. | Nov 2022
Edisto Island Frequently Asked Questions

Yes, 52 of our Edisto Island homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 115 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Edisto Island, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.