Mosquito Lagoon Cabin Rentals

Compare 45 vacation rentals.
USA > Florida > Mosquito Lagoon

Make Mosquito Lagoon your next getaway

Tucked between New Smyrna Beach and Cape Canaveral, Mosquito Lagoon is one of Florida’s best-kept secrets—a serene, wildlife-rich estuary where saltwater channels, seagrass beds, and mangrove islands invite you to slow down and soak in the natural beauty of the Sunshine State.

Explore Mosquito Lagoon condo rentals, house rentals, townhouses, and more

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Condo rentals

View 30 Condo rentals
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House rentals

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Townhouses

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Popular amenities for Mosquito Lagoon vacation rentals

Popular
Dog-friendly Hot tub Internet
Wait n' Sea
2 Bedroom | 2 Bath | Sleeps 5

Wait n' Sea - New Smyrna Beach, FL

$194 avg / night
(excludes fees and taxes)
4.63 (27)
Winding Waterways
2 Bedroom | 2 Bath | Sleeps 6

Winding Waterways - New Smyrna Beach, FL

$131 avg / night
(excludes fees and taxes)
4.68 (44)
Pelican 303E
2 Bedroom | 2.5 Bath | Sleeps 6 (5 Adults Max)

Pelican 303E - New Smyrna Beach, FL

$260 avg / night
(excludes fees and taxes)
3.88 (50)
The Blue Horizon Estate
6 Bedroom | 6 Bath | Sleeps 14

The Blue Horizon Estate - Edgewater, FL

$1,391 avg / night
(excludes fees and taxes)
4.75 (4)
Oceanwalk 10-203
3 Bedroom | 2 Bath | Sleeps 10

Oceanwalk 10-203 - New Smyrna Beach, FL

$201 avg / night
(excludes fees and taxes)
4.33 (15)

View 40 more homes

Recent Mosquito Lagoon guest reviews

Cute villa. Private and quiet. Close to the beach. We would rent here again!
Kristie, L. | Jul 2025
I loved the largeness of the kitchen. We were able to fit a lot of our groceries and stuff in there. They were plenty of utensils and pots and pans and all that we were able to cook any meals we wanted the lounging area was very, very comfortable the couch the TV works great. The only thing where we are there is that they were painting so they had to take away your patio furniture but you know we don’t really sit out there with the mosquitoes much anyway so the Bed in the master bedroom is extremely comfortable and overall we had a very pleasant time and I would go again
Mary Ann J. | Jul 2025
Convenience to beach.
William C. | Jul 2025
Mosquito Lagoon vacation rental FAQ

Yes, 10 of our Mosquito Lagoon homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 45 of our Mosquito Lagoon vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Mosquito Lagoon vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Mosquito Lagoon team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Mosquito Lagoon, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
Vacasa Guest Value Prop Icon check-in
Seamless check-in
Vacasa Guest Value Prop Icons cleaning
Professional cleaning

Why vacation in Mosquito Lagoon?

If you're looking for quiet mornings, calm waters, and a true getaway from the crowds, Mosquito Lagoon delivers. With seemingly endless waterways and nearby access to the Canaveral National Seashore, this area is ideal for anyone who prefers a paddleboard to a beach chair and sunrises over nightlife. With a vacation rental nearby, you’ll have front-row access to Florida’s untamed coastal beauty—and plenty of space to unwind.

Things to do around Mosquito Lagoon

Where to stay near Mosquito Lagoon

From rustic cabins to charming waterfront cottages, vacation rentals near Mosquito Lagoon offer a peaceful retreat with easy access to the water.