Lower Keys, FL Vacation Rentals

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USA > Florida > Lower Keys, FL

Make Lower Keys, FL your next getaway—choose from 299 great vacation rentals

Explore our Lower Keys vacation rentals

Explore Lower Keys, FL house rentals, condo rentals, duplexes, and more


House rentals

View 142 House rentals

Condo rentals

View 87 Condo rentals


View 22 Duplexes

Lower Keys, FL vacation rentals for every getaway

Dog-friendly Hot tub Internet
Sunrise Suites - Barbados Suite 204
2 Bedroom | 2 Bath | Sleeps 6

Sunrise Suites - Barbados Suite 204 - Key West, FL

$308 avg / night
Tropical Sabbatical
1 Bedroom | 2 Bath | Sleeps 6

Tropical Sabbatical - Cudjoe Key, FL

$240 avg / night
Pelico Paradise
5 Bedroom | 3.5 Bath | Sleeps 10

Pelico Paradise - Sugarloaf Key, FL

$515 avg / night
Sunrise Suites - Saint Lucia Suite 201
2 Bedroom | 2 Bath | Sleeps 6

Sunrise Suites - Saint Lucia Suite 201 - Key West, FL

$331 avg / night
Sunrise Suites - Jamaica Suite 102
2 Bedroom | 2 Bath | Sleeps 6

Sunrise Suites - Jamaica Suite 102 - Key West, FL

$326 avg / night

View 294 more homes

Recent Lower Keys, FL vacation rental reviews

Great spot for 2 couples or a family. 2 bed, 2 bath with shared living space and full kitchen with in home washer/dryer. Very clean. Only $20-30 Uber/Lyft/taxi ride to Duval street.
Brooke B. | Aug 2022
I loved that it was secluded but easy to get to. Everything was the way the listing said. I slept well and the refrigerator worked great.
Edward S. | Aug 2022
Michael T. | Aug 2022
Lower Keys, FL Frequently Asked Questions

Yes, 124 of our Lower Keys, FL homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 298 of our Lower Keys, FL vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our Lower Keys, FL vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Lower Keys, FL team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Lower Keys, FL, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

When you’re looking for that perfect Florida Keys vacation rental, be sure to browse our Lower Keys beach houses and condos. Spanning the length of the legendary Overseas Highway, the Lower Keys area begins around Marathon and stretches to the southwest all the way to Key West. Whether you’re visiting for a weekend or the entire winter, a visit to a Lower Keys vacation rental guarantees tropical bliss.

Marathon and Key Colony Beach: the gateway to the Lower Keys

The town of Marathon, which technically encompasses several keys, is one of the most popular destinations in the Florida Keys. Key Colony Beach, the hub of Marathon, is home to several beautiful stretches of shoreline, as well as plenty of docks, restaurants, and luxurious vacation rentals to choose from. Like everywhere in the Lower Keys, the fishing and snorkeling surrounding Marathon are superb, so don’t be afraid to get out on the waves!

Cudjoe Key, the Torch Keys, and Sugarloaf Key

Cross the Seven Mile Bridge, and you’ll find the hidden gems of the Lower Keys: the Torch Keys, Cudjoe Key, and Sugarloaf Key. These less populous parts of the keys are home to some of our most secluded and beautiful Florida Keys vacation rentals, some of which are beachfront---an amenity in hot demand in the Lower Keys. Find your own little corner of paradise here, and you’re just a short car trip away from the hustle and bustle of Key West or Marathon.

Key West: the southern end of the Lower Keys

Colloquially recognized as the United States’ Southernmost Point, Key West is a historic and beautiful spot for a Keys getaway. Many of our Key West vacation rentals boast private pools, luxurious interiors, spacious patios, and rich history. Duval Street is the hub of most of the town’s action, with plenty of shopping, dining, and entertainment choices. Book a fishing excursion or sailing charter and enjoy the crystal-blue waters that surround you, or rent snorkeling gear and experience the area’s renowned coral reefs. A Key West vacation rental is the perfect place to spend the whole winter---snowbirds are welcome!

No matter where you're headed in the Lower Keys, we have a picturesque vacation home waiting for you. Book today!