Lower Keys, FL Vacation Rentals

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USA > Florida > Lower Keys, FL

Make Lower Keys, FL your next getaway—choose from 255 great vacation rentals

Explore our Lower Keys vacation rentals

Explore Lower Keys, FL house rentals, condo rentals, duplexes, and more

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House rentals

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Condo rentals

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Duplexes

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Lower Keys, FL vacation rentals for every getaway

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Dog-friendly Hot tub Internet
Duck Key Retreat Villa #5105 3D Tour
2 Bedroom | 1.5 Bath | Sleeps 6

Duck Key Retreat Villa #5105 - Duck Key, FL

From $375
Duck Key Getaway- VILLA 8202 3D Tour
3 Bedroom | 2.5 Bath | Sleeps 8

Duck Key Getaway- VILLA 8202 - Duck Key, FL

From $206
Sunrise Suites - Barbados Suite 204 3D Tour
2 Bedroom | 2 Bath | Sleeps 6

Sunrise Suites - Barbados Suite 204 - Key West, FL

From $211
Duck Key Oasis #7213 3D Tour
3 Bedroom | 2.5 Bath | Sleeps 8

Duck Key Oasis #7213 - Duck Key, FL

From $649
Sunrise Suites - Saint Croix Suite 212 3D Tour
2 Bedroom | 2 Bath | Sleeps 6

Sunrise Suites - Saint Croix Suite 212 - Key West, FL

From $141

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Recent Lower Keys, FL vacation rental reviews

The room was perfect and very well maintained. The people were friendly and fun to hang around.
Patrick R. | Dec 2021
The condo was very clean , it had everything you could possibly need for a great stay!
Edward O. | Dec 2021
The house was well maintained and appeared to be recently remodeled. Kitchen had everything we needed, beds were comfy. The pool/deck area was beautiful and we spent much of our stay in and around the pool. Easy walk to restaurants, bars and grocery store. I will definitely try to stay here again!
Susan S. | Dec 2021

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

When you’re looking for that perfect Florida Keys vacation rental, be sure to browse our Lower Keys beach houses and condos. Spanning the length of the legendary Overseas Highway, the Lower Keys area begins around Marathon and stretches to the southwest all the way to Key West. Whether you’re visiting for a weekend or the entire winter, a visit to a Lower Keys vacation rental guarantees tropical bliss.

Marathon and Key Colony Beach: the gateway to the Lower Keys


The town of Marathon, which technically encompasses several keys, is one of the most popular destinations in the Florida Keys. Key Colony Beach, the hub of Marathon, is home to several beautiful stretches of shoreline, as well as plenty of docks, restaurants, and luxurious vacation rentals to choose from. Like everywhere in the Lower Keys, the fishing and snorkeling surrounding Marathon are superb, so don’t be afraid to get out on the waves!

Cudjoe Key, the Torch Keys, and Sugarloaf Key


Cross the Seven Mile Bridge, and you’ll find the hidden gems of the Lower Keys: the Torch Keys, Cudjoe Key, and Sugarloaf Key. These less populous parts of the keys are home to some of our most secluded and beautiful Florida Keys vacation rentals, some of which are beachfront---an amenity in hot demand in the Lower Keys. Find your own little corner of paradise here, and you’re just a short car trip away from the hustle and bustle of Key West or Marathon.

Key West: the southern end of the Lower Keys


Colloquially recognized as the United States’ Southernmost Point, Key West is a historic and beautiful spot for a Keys getaway. Many of our Key West vacation rentals boast private pools, luxurious interiors, spacious patios, and rich history. Duval Street is the hub of most of the town’s action, with plenty of shopping, dining, and entertainment choices. Book a fishing excursion or sailing charter and enjoy the crystal-blue waters that surround you, or rent snorkeling gear and experience the area’s renowned coral reefs. A Key West vacation rental is the perfect place to spend the whole winter---snowbirds are welcome!

No matter where you're headed in the Lower Keys, we have a picturesque vacation home waiting for you. Book today!