Isle of Palms Vacation Rentals

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USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway—choose from 76 great vacation rentals

Our Isle of Palms vacation rentals are ready to host your getaway to South Carolina’s beautiful sandy beaches. You’ll find tranquility here, set back from the hustle and bustle, while still being within easy reach of Charleston.

Explore Isle of Palms villas, house rentals, condo rentals, and more



View 46 Villas

House rentals

View 19 House rentals

Condo rentals

View 9 Condo rentals

Isle of Palms vacation rentals for every getaway

Dog-friendly Hot tub Internet
Sea Cabin 347-C 3D Tour
1 Bedroom | 1 Bath | Sleeps 4

Sea Cabin 347-C - Isle of Palms, SC

From $99
Seacabin Villa 341-C
1 Bedroom | 1 Bath | Sleeps 6

Seacabin Villa 341-C - Isle of Palms, SC

From $119
Port O'Call E-203 3D Tour
1 Bedroom | 1 Bath | Sleeps 4

Port O'Call E-203 - Isle of Palms, SC

From $145
Sea Shell 4 3D Tour
4 Bedroom | 3.5 Bath | Sleeps 10

Sea Shell 4 - Isle of Palms, SC

From $167
Sea Cabin 137-C 3D Tour
1 Bedroom | 1 Bath | Sleeps 6

Sea Cabin 137-C - Isle of Palms, SC

From $77

View 71 more homes

Recent Isle of Palms vacation rental reviews

The location of this rental to the beach was very good; a walk of about 5 minutes. However, there were issues that were unacceptable and would eliminate this rental for us in the future. The laundry was across the street in a location that we could not even park our car. In order to do laundry, we would have to carry it across the avenue and back. The mattresses in the second bedroom were so uncomfortable, one of the guests had to sleep on the sofa, which wasn't much better. The TV in the second bedroom didn't work, and there were no instructions on how to get it to work. The sliding glass doors and outside screen door did not have locks and the bar installed as a barrier was broken. Although it was mentioned in the description of the unit that there were stairs and no elevator, carrying luggage, groceries and supplies up three flights of stairs is something I do not wish to do again on vacation. The location was close to shops and big box stores and a short ride to Charleston, which was a plus. If you can tolerate all the other inconveniences and issues, this would be an acceptable rental for you. I will not stay in this area again in the future.
Bonnie G. | Oct 2021
Loved our stay. Location to beech fantastic.
Gene B. | Oct 2021
Nice time and great yard.
Sam W. | Oct 2021

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Where are our Isle of Palms vacation rentals?

The city of Isle of Palms rests on a barrier island of the same name, just 18 miles from Charleston and about 130 miles from Columbia. These long stretches of beach provide a natural habitat for sea turtles—if you’re lucky, you just may catch local licensed professionals assisting these tiny creatures in their journey to the ocean.

Things to do near our Isle of Palms beach rentals

There are a number of ways to explore the area around our Isle of Palms beach house rentals and condos. Cruise the streets on a moped, courtesy of Port City Mopeds, as you stop along the boutique shops and ice creameries. In fact, the island is very walkable, and you’ll see many pedestrians, cyclists, and even golf carts roaming the quiet streets.

When it’s time to get in the water, head to Isle of Palms County Park, where you’ll find a grassy patch with a playground, picnic tables, and parking. A short boardwalk connects you to soft sands and warm, gentle waves perfect for splashing or for kids learning to surf. Spend your days building sandcastles, bingeing your newest page turner, or enjoying a homemade picnic whipped up in your Isle of Palms vacation rental. 

If you just can’t get enough of that blue ocean, a number of local companies provide fishing charters, boat rentals, and even eco-tours. Whether you’re looking for a romantic sailboat charter at sunset, or an informational family excursion exploring nearby barrier islands, there’s something for every taste.

A trip to adjacent Sullivan’s Island is a must for history buffs, where you can tour Fort Moultrie, which played a role in both the American Revolution and the Civil War. Afterwards, head to the nearby beaches or to Poe’s Tavern, a literary-themed eatery with delicious burgers and craft beers.

Be sure to stop by the seasonal Isle of Palms Farmers’ Market for local produce, baked goods, preserves, and to catch some live entertainment by local musicians. Our Isle of Palms beach rentals and condos feature fully-equipped kitchens, so you can try your hand at a new recipe with local ingredients or fresh-caught seafood. 

If you want to pamper yourself you can head to Beach House Spa, located inside a cozy cottage. Treat yourself to a massage, body scrub, or facial—or all three—and feel the worries of everyday life melt away. A visit to nearby Charleston will surround you with even more luxury, from high-end dining to designer clothing stores.

There’s so much to do and see in Isle of Palms. Whether you’re visiting for the gorgeous beaches, to be near the hustle and bustle of Charleston, or just for some relaxation, our Isle of Palms vacation rentals are ready to host your getaway. Browse our collection of beautiful homes today.