Isle of Palms Rentals

Compare 69 vacation rentals.
USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway

Our Isle of Palms vacation rentals are ready to host your getaway to South Carolina’s beautiful sandy beaches. You’ll find tranquility here, set back from the hustle and bustle, while still being within easy reach of Charleston.

Explore Isle of Palms house rentals, villas, condo rentals, and more


House rentals

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View 27 Villas

Condo rentals

View 13 Condo rentals

Isle of Palms vacation rentals for every getaway

Dog-friendly Hot tub Internet
Sea Cabin 337C
1 Bedroom | 1 Bath | Sleeps 4

Sea Cabin 337C - Isle of Palms, SC

$276 avg / night
Seagrove 5-A
1 Bedroom | 1 Bath | Sleeps 2

Seagrove 5-A - Isle of Palms, SC

$264 avg / night
Carolina Boulevard 808
4 Bedroom | 4.5 Bath | Sleeps 8

Carolina Boulevard 808 - Isle of Palms, SC

$1,025 avg / night
Sea Cabin 121-B
1 Bedroom | 1 Bath | Sleeps 4

Sea Cabin 121-B - Isle of Palms, SC

$214 avg / night
Sea Cabin 227-B
1 Bedroom | 1 Bath | Sleeps 4

Sea Cabin 227-B - Isle of Palms, SC

$242 avg / night

View 64 more homes

Recent Isle of Palms vacation rental reviews

Nicely laid out floor plan with plenty of room for 8 adults. Convenient to everything Wild Dunes has to offer.
Sandra O. | Feb 2024
This house is spacious and elegant, with a stunning view of the Intracoastal Waterway. It’s very nicely and comfortably furnished; everything is tasteful and attractive. There’s even some appealing art on the walls. Not to mention a pretty great little cookbook collection. The two main bathrooms (one downstairs, adjacent to the master and the other upstairs) are of note: very large, each with a large, sunken tub with a gorgeous marsh and water view. Inside, this place feels like what it clearly is (or was): someone’s gracious, year-round family home, not a tatty beach house. In other words, it is many steps above the typical short-term rental you find these days, which is furnished sparsely, cheaply, and impersonally. Outside, the sunsets from the little dock/observation platform are spectacular. Plus, it’s the next house from the end of a cul-de-sac, meaning no traffic and very, very quiet. Good privacy, although it is true the neighbor next door is impossible to ignore, wandering around the yard and driveway (which are pretty close to this yard and driveway) at various times of day, often accompanied by two dogs and often barking down his cell phone. All the glowing reviews are true. This is a large, lovely, functional, comfortable house, appealing in every way. PS Note that there is only one television, which is in the living room and it is not huge. Not a problem for us, but if you are used to short-term rentals with a big flatscreen in every bedroom, you might find this surprising.
Christopher M. | Feb 2024
Beautiful place in a beautiful location!
jennifer o. | Feb 2024
Isle of Palms vacation rental FAQ

Yes, 28 of our Isle of Palms homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 149 of our Isle of Palms vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our Isle of Palms vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Isle of Palms team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Isle of Palms, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Where are our Isle of Palms vacation rentals?

The city of Isle of Palms rests on a barrier island of the same name, just 18 miles from Charleston and about 130 miles from Columbia. These long stretches of beach provide a natural habitat for sea turtles—if you’re lucky, you just may catch local licensed professionals assisting these tiny creatures in their journey to the ocean.

Things to do near our Isle of Palms beach rentals

There are a number of ways to explore the area around our Isle of Palms beach house rentals and condos. Cruise the streets on a moped, courtesy of Port City Mopeds, as you stop along the boutique shops and ice creameries. In fact, the island is very walkable, and you’ll see many pedestrians, cyclists, and even golf carts roaming the quiet streets.

When it’s time to get in the water, head to Isle of Palms County Park, where you’ll find a grassy patch with a playground, picnic tables, and parking. A short boardwalk connects you to soft sands and warm, gentle waves perfect for splashing or for kids learning to surf. Spend your days building sandcastles, bingeing your newest page turner, or enjoying a homemade picnic whipped up in your Isle of Palms vacation rental. 

If you just can’t get enough of that blue ocean, a number of local companies provide fishing charters, boat rentals, and even eco-tours. Whether you’re looking for a romantic sailboat charter at sunset, or an informational family excursion exploring nearby barrier islands, there’s something for every taste.

A trip to adjacent Sullivan’s Island is a must for history buffs, where you can tour Fort Moultrie, which played a role in both the American Revolution and the Civil War. Afterwards, head to the nearby beaches or to Poe’s Tavern, a literary-themed eatery with delicious burgers and craft beers.

Be sure to stop by the seasonal Isle of Palms Farmers’ Market for local produce, baked goods, preserves, and to catch some live entertainment by local musicians. Our Isle of Palms beach rentals and condos feature fully-equipped kitchens, so you can try your hand at a new recipe with local ingredients or fresh-caught seafood. 

If you want to pamper yourself you can head to Beach House Spa, located inside a cozy cottage. Treat yourself to a massage, body scrub, or facial—or all three—and feel the worries of everyday life melt away. A visit to nearby Charleston will surround you with even more luxury, from high-end dining to designer clothing stores.

There’s so much to do and see in Isle of Palms. Whether you’re visiting for the gorgeous beaches, to be near the hustle and bustle of Charleston, or just for some relaxation, our Isle of Palms vacation rentals are ready to host your getaway. Browse our collection of beautiful homes today.