Isle of Palms Vacation Rentals

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USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway—choose from 70 great vacation rentals

Our Isle of Palms vacation rentals are ready to host your getaway to South Carolina’s beautiful sandy beaches. You’ll find tranquility here, set back from the hustle and bustle, while still being within easy reach of Charleston.

Explore Isle of Palms villas, house rentals, condo rentals, and more



View 42 Villas

House rentals

View 20 House rentals

Condo rentals

View 7 Condo rentals

Isle of Palms vacation rentals for every getaway

Dog-friendly Hot tub Internet
Ocean Club 1301 3D Tour
3 Bedroom | 3.5 Bath | Sleeps 8

Ocean Club 1301 - Isle of Palms, SC

From $300
Sea Cabin 306-A 3D Tour
1 Bedroom | 1 Bath | Sleeps 6

Sea Cabin 306-A - Isle of Palms, SC

From $100
Sea Cabin 347-C 3D Tour
1 Bedroom | 1 Bath | Sleeps 4

Sea Cabin 347-C - Isle of Palms, SC

From $99
Port O'Call C-201 3D Tour
1 Bedroom | 1 Bath | Sleeps 3

Port O'Call C-201 - Isle of Palms, SC

From $109
Ocean Boulevard 714 3D Tour
6 Bedroom | 4 Bath | Sleeps 14

Ocean Boulevard 714 - Isle of Palms, SC

From $594

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Recent Isle of Palms vacation rental reviews

great location. walk to everything
john m. | Jan 2022
Our apartment was roomy and the view of the ocean was perfect! It was very clean and the Vacasa staff was always helpful.
Kathleen N. | Jan 2022
We loved staying here! It is about 25-30 minutes from downtown Charleston and right on the beach. We already booked it again for later this year.
Alicia L. | Jan 2022

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Where are our Isle of Palms vacation rentals?

The city of Isle of Palms rests on a barrier island of the same name, just 18 miles from Charleston and about 130 miles from Columbia. These long stretches of beach provide a natural habitat for sea turtles—if you’re lucky, you just may catch local licensed professionals assisting these tiny creatures in their journey to the ocean.

Things to do near our Isle of Palms beach rentals

There are a number of ways to explore the area around our Isle of Palms beach house rentals and condos. Cruise the streets on a moped, courtesy of Port City Mopeds, as you stop along the boutique shops and ice creameries. In fact, the island is very walkable, and you’ll see many pedestrians, cyclists, and even golf carts roaming the quiet streets.

When it’s time to get in the water, head to Isle of Palms County Park, where you’ll find a grassy patch with a playground, picnic tables, and parking. A short boardwalk connects you to soft sands and warm, gentle waves perfect for splashing or for kids learning to surf. Spend your days building sandcastles, bingeing your newest page turner, or enjoying a homemade picnic whipped up in your Isle of Palms vacation rental. 

If you just can’t get enough of that blue ocean, a number of local companies provide fishing charters, boat rentals, and even eco-tours. Whether you’re looking for a romantic sailboat charter at sunset, or an informational family excursion exploring nearby barrier islands, there’s something for every taste.

A trip to adjacent Sullivan’s Island is a must for history buffs, where you can tour Fort Moultrie, which played a role in both the American Revolution and the Civil War. Afterwards, head to the nearby beaches or to Poe’s Tavern, a literary-themed eatery with delicious burgers and craft beers.

Be sure to stop by the seasonal Isle of Palms Farmers’ Market for local produce, baked goods, preserves, and to catch some live entertainment by local musicians. Our Isle of Palms beach rentals and condos feature fully-equipped kitchens, so you can try your hand at a new recipe with local ingredients or fresh-caught seafood. 

If you want to pamper yourself you can head to Beach House Spa, located inside a cozy cottage. Treat yourself to a massage, body scrub, or facial—or all three—and feel the worries of everyday life melt away. A visit to nearby Charleston will surround you with even more luxury, from high-end dining to designer clothing stores.

There’s so much to do and see in Isle of Palms. Whether you’re visiting for the gorgeous beaches, to be near the hustle and bustle of Charleston, or just for some relaxation, our Isle of Palms vacation rentals are ready to host your getaway. Browse our collection of beautiful homes today.