Isle of Palms Rentals

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USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway

Looking for a peaceful getaway to South Carolina’s sandy beaches? Our Isle of Palms vacation rentals offer tranquility, set apart from the hustle and bustle, but still close enough to enjoy the charm of Charleston. Whether you're looking for family fun or a romantic escape, the Isle of Palms has something for everyone.

Explore Isle of Palms house rentals, villas, condo rentals, and more

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House rentals

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Villas

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Condo rentals

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Popular amenities for Isle of Palms vacation rentals

Popular
Dog-friendly Hot tub Internet
Port O'Call C-303
1 Bedroom | 1 Bath | Sleeps 2

Port O'Call C-303 - Isle of Palms, SC

$201 avg / night
(excludes fees and taxes)
3.83 (83)
40 Lagoon Villa
2 Bedroom | 2 Bath | Sleeps 6

40 Lagoon Villa - Isle of Palms, SC

$286 avg / night
(excludes fees and taxes)
5.0 (1)
Port O' Call D-103
1 Bedroom | 1 Bath | Sleeps 5

Port O' Call D-103 - Isle of Palms, SC

$268 avg / night
(excludes fees and taxes)
4.55 (33)
Sea Cabin 347-C
1 Bedroom | 1 Bath | Sleeps 2

Sea Cabin 347-C - Isle of Palms, SC

$266 avg / night
(excludes fees and taxes)
4.45 (88)
Sea Cabin 121-B
1 Bedroom | 1 Bath | Sleeps 4

Sea Cabin 121-B - Isle of Palms, SC

$193 avg / night
(excludes fees and taxes)
4.2 (20)

View 52 more homes

Recent Isle of Palms guest reviews

Loved this place - like 100 yards from the beach entrance! Perfect for a bachelorette or a family vacation.
MK P. | May 2025
This house was what we were looking for. Close enough to the beach but not too close to where we couldn't afford it. It had the correct amenities for what we could do. It's back in wild dunes so it's quiet, but also close enough to IOP, Sullivan's island and Charleston if you want to enjoy the people, food, atmosphere etc. of all that. Some folks have complained about the distance to the beach, it's a 5-minute walk at most. Plenty close enough and it's on a nice street. Furniture was comfortable, house was clean porch is very nice!! I can't think of anything to complain about.
Christopher B. | May 2025
The house was truly beautiful; we absolutely adored the decor and the layout was great. Our group of nine girls found all the bedrooms very comfortable, and while we didn't have children on our trip, we felt the bunk rooms would be more appropriate for younger guests or young adults. The kitchen was exceptionally well-stocked with tons of cooking supplies, glassware, and everything we needed. We loved the quiet and beautiful neighborhood, perfect for walks, and being just minutes from the 52nd beach access was fantastic. We highly recommend renting beach chairs and umbrellas from a local company; it was so convenient having them set up for us before 10 AM each day, saving us the hassle of carrying everything. While we loved everything about the interior of the house and its location, our one disappointment was the back deck and pool area. It could have been significantly better maintained. There were children's toys scattered everywhere, the pool was noticeably unclean with debris, and leaves covered the deck. The back deck furniture was also disorganized and looked sloppy. We believe the owners should seriously consider the upkeep of the backyard and pool area, as it was unfortunately an eyesore and not enjoyable for relaxation.
Taylor M. | May 2025
Isle of Palms vacation rental FAQ

Yes, 25 of our Isle of Palms homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 104 of our Isle of Palms vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Isle of Palms vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Isle of Palms team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Isle of Palms, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
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Seamless check-in
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Professional cleaning

Explore Isle of Palms, SC

Nestled on a beautiful barrier island, Isle of Palms is just 18 miles from Charleston and about 130 miles from Columbia. This idyllic location is perfect for beachgoers and nature lovers alike. The island's long stretches of beach are home to sea turtles, and if you’re lucky, you might witness local professionals helping these tiny creatures make their way to the ocean.

Things to do in Isle of Palms, SC

From beach fun to exploring nearby islands, there's no shortage of activities to enjoy during your stay.

Where is Isle of Palms, SC?

Located just off the coast of South Carolina, Isle of Palms is a barrier island near Charleston. It offers easy access to both the serene beauty of the ocean and the vibrant culture of Charleston, making it an ideal spot for vacationers looking to experience the best of both worlds.

Book an Isle of Palms vacation rental

Whether you're visiting for the beaches, the history, or just to unwind, our Isle of Palms vacation rentals provide the perfect retreat. With a range of homes featuring ocean views, spacious patios, and family-friendly amenities, you're sure to find a spot that fits your getaway vision. Browse our collection of Isle of Palms vacation homes and get ready for a relaxing escape on South Carolina’s coast.

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