Isle of Palms Rentals

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USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway

Looking for a peaceful getaway to South Carolina’s sandy beaches? Our Isle of Palms vacation rentals offer tranquility, set apart from the hustle and bustle, but still close enough to enjoy the charm of Charleston. Whether you're looking for family fun or a romantic escape, the Isle of Palms has something for everyone.

Explore Isle of Palms house rentals, villas, condo rentals, and more

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House rentals

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Villas

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Condo rentals

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Popular amenities for Isle of Palms vacation rentals

Popular
Dog-friendly Hot tub Internet
Port O'Call C-303
1 Bedroom | 1 Bath | Sleeps 2

Port O'Call C-303 - Isle of Palms, SC

$200 avg / night
(excludes fees and taxes)
3.83 (83)
40 Lagoon Villa
2 Bedroom | 2 Bath | Sleeps 6

40 Lagoon Villa - Isle of Palms, SC

$284 avg / night
(excludes fees and taxes)
5.0 (1)
Sea Cabin 227-B
1 Bedroom | 1 Bath | Sleeps 4

Sea Cabin 227-B - Isle of Palms, SC

$232 avg / night
(excludes fees and taxes)
4.28 (18)
Port O' Call D-103
1 Bedroom | 1 Bath | Sleeps 5

Port O' Call D-103 - Isle of Palms, SC

$267 avg / night
(excludes fees and taxes)
4.55 (33)
Tidewater H-203
2 Bedroom | 2 Bath | Sleeps 6

Tidewater H-203 - Isle of Palms, SC

$311 avg / night
(excludes fees and taxes)
4.21 (57)

View 52 more homes

Recent Isle of Palms guest reviews

We loved everything about the cabin. Very clean,stocked with everything you would possibly need. I loved that it had beach chairs and umbrella. Best placed I have ever stayed in all my travels. I recommend this place and I will stay there next time we come to Isles of Palm.
Walter C. | May 2025
This property was amazing for my beach trip this past week. Every room was cozy and well stocked with blankets and pillows and every bedroom had a private full bathroom! The living area was comfy and nice, the galley kitchen was well stocked (just bring your own can opener and teapot if you need those things), and our favorite spot was the screened in deck! The pool was right across from the property and the beach was a less than 10 minute walk away. Amenities at the resort hotel (Coastal Crust was so good) were a 20 minute walk but you could also drive there! If you forgot any beach supplies there were chairs, umbrellas, and toys in the garage! I would 100% book this spot again.
Alexia K. | May 2025
This condo was exactly as advertised! Couldn’t have been better. Screened porch looks over the pool and the ocean is just beyond the pool! It was very clean (and I am very picky). The beds were very comfortable. Kitchen is nicely equipped even though I did no cooking. The owners have done an excellent job making sure you feel at home. I love the swing on the screened porch. Very relaxing! I would definitely stay here again!
Donna K. | May 2025
Isle of Palms vacation rental FAQ

Yes, 24 of our Isle of Palms homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 103 of our Isle of Palms vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Isle of Palms vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Isle of Palms team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Isle of Palms, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
Vacasa Guest Value Prop Icon check-in
Seamless check-in
Vacasa Guest Value Prop Icons cleaning
Professional cleaning

Explore Isle of Palms, SC

Nestled on a beautiful barrier island, Isle of Palms is just 18 miles from Charleston and about 130 miles from Columbia. This idyllic location is perfect for beachgoers and nature lovers alike. The island's long stretches of beach are home to sea turtles, and if you’re lucky, you might witness local professionals helping these tiny creatures make their way to the ocean.

Things to do in Isle of Palms, SC

From beach fun to exploring nearby islands, there's no shortage of activities to enjoy during your stay.

Where is Isle of Palms, SC?

Located just off the coast of South Carolina, Isle of Palms is a barrier island near Charleston. It offers easy access to both the serene beauty of the ocean and the vibrant culture of Charleston, making it an ideal spot for vacationers looking to experience the best of both worlds.

Book an Isle of Palms vacation rental

Whether you're visiting for the beaches, the history, or just to unwind, our Isle of Palms vacation rentals provide the perfect retreat. With a range of homes featuring ocean views, spacious patios, and family-friendly amenities, you're sure to find a spot that fits your getaway vision. Browse our collection of Isle of Palms vacation homes and get ready for a relaxing escape on South Carolina’s coast.

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