Panama City Vacation Rentals

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USA > Florida > Panama City

Make Panama City your next getaway—choose from 18 great vacation rentals

Panama City embodies the beauty and excitement of The Sunshine State! There's something for the adventurer and beach bum in everyone at a vacation rental in Panama City. The city is boarded by St. Andrews Bay and the Gulf of Mexico within the famous Florida Panhandle. Vacationers can learn about the city's rich heritage in Historical St. Andrews, which is home to fishing vessels, quaint boutiques, and local eateries like the Shrimpboat Restaurant serving up unbeatable local fare!

Explore Panama City condo rentals, house rentals, penthouses, and more


Condo rentals

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House rentals

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Panama City vacation rentals for every getaway

Dog-friendly Hot tub Internet
Celadon Beach 1607
1 Bedroom | 2 Bath | Sleeps 6

Celadon Beach 1607 - Panama City, FL

$184 avg / night
Splash Resort 1606W
2 Bedroom | 2 Bath | Sleeps 6

Splash Resort 1606W - Panama City, FL

$283 avg / night
Splash Resort 2001W
2 Bedroom | 2 Bath | Sleeps 10

Splash Resort 2001W - Panama City, FL

$281 avg / night
Boardwalk Beach Resort 1006
1 Bedroom | 1 Bath | Sleeps 6

Boardwalk Beach Resort 1006 - Panama City, FL

$187 avg / night
The Inn at St. Thomas Square 1311B
1 Bedroom | 1 Bath | Sleeps 4

The Inn at St. Thomas Square 1311B - Panama City, FL

$152 avg / night

View 13 more homes

Recent Panama City vacation rental reviews

Room was clean and view was amazing! Loved everything about our stay!
Kelly T. | Feb 2023
Nice place and of course convenient to St. Andrew's. Great place to stay! My uncle and aunts place is still across the street on the bay from the 50's.
John E. | Jan 2023
The condo was located close proximity to attractions. The size of the condo was perfect for a family of 3. The beachfront view was amazing.
Ira H. | Jan 2023
Panama City vacation rental FAQ

Yes, 46 of our Panama City homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 496 of our Panama City vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our Panama City vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Panama City team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Panama City, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Arts and culture in Panama City

Our selection of vacation rentals are located in an area brimming with arts and culture events! Watch a Broadway musical or classic rock concert at the Marina Civic Center or watch an impressive community theater production at the iconic Martin Theatre, which was originally built in 1936. The Paul Brent Gallery offers fine art, gifts, and home decor, or make a day of it with A Taste of Panama City Food Tours, which offer guided historical and culinary tours throughout the city.

Panama City attractions

All roads near your Panama City vacation rental lead to St. Andrews State Park! The park represents Florida's finest with emerald green waters and white sand beaches. This former military reservation offers pristine swimming, scuba and snorkeling, kayaking, and canoeing along the Gulf of Mexico and Grand Lagoon. The park offers two fishing piers, natural trails, and plenty picnic pavilions for a day in the sun!

Get hands-on at the Science & Discovery Center of Northwest Florida, which offers interactive science, technology, and history exhibits. Downtown Panama City is abuzz with live bands, bars, and shopping districts! The city truly comes alive the first Friday night of every month (held from March to November) during Friday Fest, a celebration of live music, food, and fun.

Family day trips from Panama City

For even more family fun and adventure, head ten miles west to the gorgeous sugar-sand Panama City Beach, where you can ride the roller coaters at the Miracle Strip Amusement Park, bob in the wave pool at Shipwreck Island Waterpark, and view the obscure at Ripley's Believe It or Not! Adventurous families can discover wildlife in the Florida Panhandle, including the reptiles, sea lions, dolphins and more at Gulf World Marine Park,  and the world's largest and most exotic cats are on view at Bear Creek Feline Center.

With a little more time to spare, go for a scenic coastal drive along 30A, exploring small beach towns and checking out the stunning views of the ocean and eclectic atmosphere in each distinct area.

Whether you're traveling as a family, a group of friends, or a couple, a stay in one of our vacation homes in Panama City gives you the best of the Florida Panhandle in one complete package. Choose your favorite today!