Isle of Palms Vacation Rentals

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USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway—choose from 80 great vacation rentals

Our Isle of Palms vacation rentals are ready to host your getaway to South Carolina’s beautiful sandy beaches. You’ll find tranquility here, set back from the hustle and bustle, while still being within easy reach of Charleston.

Explore Isle of Palms villas, house rentals, condo rentals, and more



View 47 Villas

House rentals

View 22 House rentals

Condo rentals

View 9 Condo rentals

Isle of Palms vacation rentals for every getaway

Dog-friendly Hot tub Internet
Port O'Call E-203 3D Tour
1 Bed | 1 Bath | Sleeps 4

Port O'Call E-203 - Isle of Palms, SC

From $168
Seagrove 5-A 3D Tour
1 Bed | 1 Bath | Sleeps 4

Seagrove 5-A - Isle of Palms, SC

From $136
Lagoon Villa 24 3D Tour
2 Bed | 2 Bath | Sleeps 6

Lagoon Villa 24 - Isle of Palms, SC

From $109
Seacabin Villa 230-B 3D Tour
1 Bed | 1 Bath | Sleeps 4

Seacabin Villa 230-B - Isle of Palms, SC

From $155
Sea Cabin 342-C 3D Tour
1 Bed | 1 Bath | Sleeps 3

Sea Cabin 342-C - Isle of Palms, SC

From $180

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Recent Isle of Palms vacation rental reviews

Cozy condo with lovely view of the water and short walk to the beach. Could use better housekeeping and better kitchen cookware. Our family of four ate out every night but would have been hard pressed to prepare a dinner with available pots and kitchen tools. Enjoyed the updated kitchen and baths but living room furniture could use updating....stained sofa, etc. No beach equipment provided by owner but some thoughtful previous guest did leave two beach chairs which we used. Umbrella and additional beach chairs had to be rented. All in all though, a comfortable stay.
Jacqueline R. | Jul 2021
Beautifully furnished and very clean. Wonderful views of pool and ocean.
Ellen C. | Jul 2021
Location is great and is just a short walk to the beach. Unit was clean on arrival and in decent condition. The couch is gross. It’s hard, uncomfortable, and filthy. PLEASE REPLACE THAT POOR COUCH. The kids had no complaints about the twin beds. The queen was super squishy and comfy with the mattress topper on but if you like a firm bed you are out of luck. Lots of fans. The big eyes on the stove don’t fit so it pretty much makes cooking impossible because your pans are sliding off. This is the second unit we have rented in the complex. Probably wouldn’t do this one again because the was nicer.
Candace S. | Jul 2021

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Where are our Isle of Palms vacation rentals?

The city of Isle of Palms rests on a barrier island of the same name, just 18 miles from Charleston and about 130 miles from Columbia. These long stretches of beach provide a natural habitat for sea turtles—if you’re lucky, you just may catch local licensed professionals assisting these tiny creatures in their journey to the ocean.

Things to do near our Isle of Palms beach rentals

There are a number of ways to explore the area around our Isle of Palms beach house rentals and condos. Cruise the streets on a moped, courtesy of Port City Mopeds, as you stop along the boutique shops and ice creameries. In fact, the island is very walkable, and you’ll see many pedestrians, cyclists, and even golf carts roaming the quiet streets.

When it’s time to get in the water, head to Isle of Palms County Park, where you’ll find a grassy patch with a playground, picnic tables, and parking. A short boardwalk connects you to soft sands and warm, gentle waves perfect for splashing or for kids learning to surf. Spend your days building sandcastles, bingeing your newest page turner, or enjoying a homemade picnic whipped up in your Isle of Palms vacation rental. 

If you just can’t get enough of that blue ocean, a number of local companies provide fishing charters, boat rentals, and even eco-tours. Whether you’re looking for a romantic sailboat charter at sunset, or an informational family excursion exploring nearby barrier islands, there’s something for every taste.

A trip to adjacent Sullivan’s Island is a must for history buffs, where you can tour Fort Moultrie, which played a role in both the American Revolution and the Civil War. Afterwards, head to the nearby beaches or to Poe’s Tavern, a literary-themed eatery with delicious burgers and craft beers.

Be sure to stop by the seasonal Isle of Palms Farmers’ Market for local produce, baked goods, preserves, and to catch some live entertainment by local musicians. Our Isle of Palms beach rentals and condos feature fully-equipped kitchens, so you can try your hand at a new recipe with local ingredients or fresh-caught seafood. 

If you want to pamper yourself you can head to Beach House Spa, located inside a cozy cottage. Treat yourself to a massage, body scrub, or facial—or all three—and feel the worries of everyday life melt away. A visit to nearby Charleston will surround you with even more luxury, from high-end dining to designer clothing stores.

There’s so much to do and see in Isle of Palms. Whether you’re visiting for the gorgeous beaches, to be near the hustle and bustle of Charleston, or just for some relaxation, our Isle of Palms vacation rentals are ready to host your getaway. Browse our collection of beautiful homes today.