Isle of Palms Vacation Rentals

Compare 80 vacation rentals. Enter your trip dates to get started.
USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway—choose from 80 great Isle of Palms Vacation Rentals

Our Isle of Palms vacation rentals are ready to host your getaway to South Carolina’s beautiful sandy beaches. You’ll find tranquility here, set back from the hustle and bustle, while still being within easy reach of Charleston.

Explore Isle of Palms villas, house rentals, condo rentals, and more

housing_type_villa.jpg

Villas

View 46 Villas
housing_type_house.jpg

House rentals

View 23 House rentals
housing_type_condo.jpg

Condo rentals

View 9 Condo rentals

Isle of Palms vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
218-B The Village 3D Tour
1 Bed | 1 Bath | Sleeps 4

218-B The Village - Isle of Palms, SC

From $102
Sea Cabin 228-B 3D Tour
1 Bed | 1 Bath | Sleeps 6

Sea Cabin 228-B - Isle of Palms, SC

From $118
Port O'Call B-302 3D Tour
1 Bed | 1 Bath | Sleeps 4

Port O'Call B-302 - Isle of Palms, SC

From $184
Palm Boulevard 2403: Upstairs 3D Tour
3 Bed | 2 Bath | Sleeps 8

Palm Boulevard 2403: Upstairs - Isle of Palms, SC

From $296
Port O'Call C-303 3D Tour
1 Bed | 1 Bath | Sleeps 4

Port O'Call C-303 - Isle of Palms, SC

From $130

View 75 more homes

Recent Isle of Palms vacation rental reviews

Check in process was extremely easy. The home was located close to beach access and the home was very clean.
Katelyn H. | May 2021
The location of this beach home on the Isle of Palms is unbelievable. Just steps away from the beach and also has a quiet pool that just a few houses share. House is large and accommodates many people. Could really use some updating on furnishings and bedding - this is the only reason I did not leave 5 stars. Our family had a wonderful time here and we would definitely return.
Constance J. | May 2021
The views of the ocean were wonderful. The unit is well maintained for the most part. The kitchen is very well equipped except for measuring spoons and cups. The master bath shower drain needs to be snaked out.
Anthony M. | May 2021

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Where are our Isle of Palms vacation rentals?

The city of Isle of Palms rests on a barrier island of the same name, just 18 miles from Charleston and about 130 miles from Columbia. These long stretches of beach provide a natural habitat for sea turtles—if you’re lucky, you just may catch local licensed professionals assisting these tiny creatures in their journey to the ocean.

Things to do near our Isle of Palms beach rentals

There are a number of ways to explore the area around our Isle of Palms beach house rentals and condos. Cruise the streets on a moped, courtesy of Port City Mopeds, as you stop along the boutique shops and ice creameries. In fact, the island is very walkable, and you’ll see many pedestrians, cyclists, and even golf carts roaming the quiet streets.

When it’s time to get in the water, head to Isle of Palms County Park, where you’ll find a grassy patch with a playground, picnic tables, and parking. A short boardwalk connects you to soft sands and warm, gentle waves perfect for splashing or for kids learning to surf. Spend your days building sandcastles, bingeing your newest page turner, or enjoying a homemade picnic whipped up in your Isle of Palms vacation rental. 

If you just can’t get enough of that blue ocean, a number of local companies provide fishing charters, boat rentals, and even eco-tours. Whether you’re looking for a romantic sailboat charter at sunset, or an informational family excursion exploring nearby barrier islands, there’s something for every taste.

A trip to adjacent Sullivan’s Island is a must for history buffs, where you can tour Fort Moultrie, which played a role in both the American Revolution and the Civil War. Afterwards, head to the nearby beaches or to Poe’s Tavern, a literary-themed eatery with delicious burgers and craft beers.

Be sure to stop by the seasonal Isle of Palms Farmers’ Market for local produce, baked goods, preserves, and to catch some live entertainment by local musicians. Our Isle of Palms beach rentals and condos feature fully-equipped kitchens, so you can try your hand at a new recipe with local ingredients or fresh-caught seafood. 

If you want to pamper yourself you can head to Beach House Spa, located inside a cozy cottage. Treat yourself to a massage, body scrub, or facial—or all three—and feel the worries of everyday life melt away. A visit to nearby Charleston will surround you with even more luxury, from high-end dining to designer clothing stores.

There’s so much to do and see in Isle of Palms. Whether you’re visiting for the gorgeous beaches, to be near the hustle and bustle of Charleston, or just for some relaxation, our Isle of Palms vacation rentals are ready to host your getaway. Browse our collection of beautiful homes today.