Isle of Palms Rentals

Compare 57 vacation rentals.
USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway

Looking for a peaceful getaway to South Carolina’s sandy beaches? Our Isle of Palms vacation rentals offer tranquility, set apart from the hustle and bustle, but still close enough to enjoy the charm of Charleston. Whether you're looking for family fun or a romantic escape, the Isle of Palms has something for everyone.

Explore Isle of Palms house rentals, villas, condo rentals, and more

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House rentals

View 22 House rentals
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Villas

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Condo rentals

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Popular amenities for Isle of Palms vacation rentals

Popular
Dog-friendly Hot tub Internet
Sea Cabin 121-B
1 Bedroom | 1 Bath | Sleeps 4

Sea Cabin 121-B - Isle of Palms, SC

$202 avg / night
4.17 (18)
Seascape 218
2 Bedroom | 2 Bath | Sleeps 6

Seascape 218 - Isle of Palms, SC

$358 avg / night
4.37 (60)
Tidewater H-202
2 Bedroom | 2 Bath | Sleeps 4

Tidewater H-202 - Isle of Palms, SC

$319 avg / night
4.26 (80)
Oceanside 212-C
2 Bedroom | 2 Bath | Sleeps 6

Oceanside 212-C - Isle of Palms, SC

$272 avg / night
4.76 (45)
Port O' Call D-103
1 Bedroom | 1 Bath | Sleeps 5

Port O' Call D-103 - Isle of Palms, SC

$267 avg / night
4.56 (32)

View 52 more homes

Recent Isle of Palms guest reviews

Great location, the yard was perfect for my dog and the home was well equipped with everything you need for a lovely vacation!
Sheryl J. | Feb 2025
Wife and I had a getaway weekend. This place was fantastic for 2.
Caleb B. | Feb 2025
Loved every moment
lacey c. | Feb 2025
Isle of Palms vacation rental FAQ

Yes, 26 of our Isle of Palms homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 108 of our Isle of Palms vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Isle of Palms vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Isle of Palms team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Isle of Palms, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
Vacasa Guest Value Prop Icon check-in
Seamless check-in
Vacasa Guest Value Prop Icons cleaning
Professional cleaning

Explore Isle of Palms, SC

Nestled on a beautiful barrier island, Isle of Palms is just 18 miles from Charleston and about 130 miles from Columbia. This idyllic location is perfect for beachgoers and nature lovers alike. The island's long stretches of beach are home to sea turtles, and if you’re lucky, you might witness local professionals helping these tiny creatures make their way to the ocean.

Things to do in Isle of Palms, SC

From beach fun to exploring nearby islands, there's no shortage of activities to enjoy during your stay.

Where is Isle of Palms, SC?

Located just off the coast of South Carolina, Isle of Palms is a barrier island near Charleston. It offers easy access to both the serene beauty of the ocean and the vibrant culture of Charleston, making it an ideal spot for vacationers looking to experience the best of both worlds.

Book an Isle of Palms vacation rental

Whether you're visiting for the beaches, the history, or just to unwind, our Isle of Palms vacation rentals provide the perfect retreat. With a range of homes featuring ocean views, spacious patios, and family-friendly amenities, you're sure to find a spot that fits your getaway vision. Browse our collection of Isle of Palms vacation homes and get ready for a relaxing escape on South Carolina’s coast.